Mesothelioma
treatment is aimed at removing the cancer cells so they do not spread beyond
the area they are located. There are different methods for defeating mesothelioma
cancer cells. A cancerous tumor can be removed through surgery. After surgery
there will likely still by cancer cells in the area that have the ability to
spread to other parts of the body. To prevent that from happening, chemotherapy
is implemented by injecting or giving the patient drugs in pill form. The
chemotherapy drugs kill the cancer cells and some healthy cells leaving the
patient feeling ill during the mesothelioma treatment.
Doctors and researchers have been coming up with alternate ways to fight
cancer. Photodynamic therapy, germ cell therapy and immunotherapy are all
different methods that can be used singularly or combined with chemotherapy.
These methods are based on exposing sensitive cancer cells to light, placing
healthy genes in the body to replace sick ones and changing the way the immune
system reacts to cancer cells.
Chemotherapy
Chemotherapy follows the removal of the cancerous tumor. When the tumor is
removed, most of the cancer is gone, however, many cancer cell can remain in
the body. The remaining cancer cells will eventually spread beyond the original
infected area and elevate the cancer to a higher stage. This is where the
chemotherapy drugs become necessary. The chemotherapy drugs can be a
combination of injections and pills that aim at killing cancer cells in the
body. As the chemotherapy slowly works, usually needing two or three sessions,
many healthy cells die in the process. To combat this problem, stem cell
transplants are used where the patient has healthy cells removed prior to the
chemotherapy. The healthy cells are placed back in the body and settle in the
bone marrow. With the new healthy cells in the body, over time the patient is
able to heal should the whole process be executed successfully.
Photodynamic
Therapy
Photodynamic therapy is a form or mesothelioma cancer treatment that is best
used for killing cancer cells that are near the surface of the body, not deep
in the organs or in a well developed stage. During the treatment, a high
intensity light drug is injected into the patient which "lights up"
the cancer cells. The cancer cells are more sensitive to light than normal
cells. The treatment is able to target and latch onto the cancer cells, making
them an easy target for doctors. With the cancer cells distinguishable from the
normal cells, a high intensity beam is shined on the cancer cells. The beam
activates the photosensitizing drug that was originally shined on to the cancer
cells and that kills the cancer cells. Photodynamic therapy is usually used
along with chemotherapy because photodynamic therapy alone may not be enough to
cure the patient of cancer.
Gene Therapy
Gene therapy is a mesothelioma treatment method that has not been approved by
the FDA for public use. Only those granted permission for a clinical trial are
eligible to receive the treatment. The main idea in gene therapy is altering
the genes in a patient's body so that sick genes can be removed and replaced or
even "turned off". If doctors can turn off a gene that is creating
cancer cells the cancer should not be able to grow. If a gene is known as sick
and may produce cancer, a healthy gene should be able to move in a take it's
place. In order to send genes to different places in the body, vectors must be
used. Our body usually uses viral vectors to more genes around. Viruses and
infections travel on these vectors. Researchers are searching for way to get
good genes to travel on viral vectors or create non-viral vectors. There is
also a "suicide gene" doctors are working on. This gene would kill
itself once a drug called prodrug takes effect on it. Until the FDA approves
gene therapy for wide spread use, most mesothelioma patients will not undergo
the treatment.
Immunotherapy
Immunotherapy is based on the idea that doctors can teach patient's immune
systems to react differently to cells produced by the body that are carrying
cancer antigens. Normally, the immune system only fights things that are
foreign to the body such as viruses. The immune system can not fight cancer
cells because it does not kills cells produced by the body even though there
are cancerous antigens on the surface of the cells. There are different approaches
to take with immunotherapy. The cancer cells can be grown and bonded with
healthy cells which create antibodies. Antibodies are normally made by the
immune system. With the new antibodies made they are placed in with the cancer
cells and they latch on and kill them. Another way is to alter the antigens on
the cancer cells so they are viewed as foreign and the immune system will kill
them. The last way is controlling the cytokines, which tell the immune system
what to do. Doctors will try and tell the cytokines to tell the immune system
to attack the cancer cells in this method.